Cohesin Can Remain Associated with Chromosomes during DNA Replication

Cohesin Can Remain Associated with Chromosomes during DNA Replication

To ensure disjunction to opposite poles during anaphase, sister chromatids must be held together following DNA replication. This is mediated by cohesin, which is thought to entrap sister DNAs inside a tripartite ring composed of its Smc and kleisin (Scc1) subunits. How such structures are created du...

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Bibliographic Details
Main Authors: James D.P. Rhodes, Judith H.I. Haarhuis, Jonathan B. Grimm, Benjamin D. Rowland, Luke D. Lavis, Kim A. Nasmyth
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
cohesin
cohesion
establishment
replication
FRAP
HaloTag
TADs
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312342

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