Ames mutagenicity, structural alerts of carcinogenicity, Hansch QSAR parameters (ClogP, CMR, MgVol), tumor site concordance/multiplicity, and tumorigenicity rank in NTP 2-year rodent studies
Since its inception in 1976, the National Toxicology Program (NTP) has conducted 594 2-year studies on rats and mice by a number of routes of administration including inhalation, feed, drinking water, dermal, and intraperitoneal injection. Of these studies, the results on 470 chemicals were of adequ...
Main Authors: | Carr J Smith, Thomas A Perfetti, Gene M Ko, Rajni Garg |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-02-01
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Series: | Toxicology Research and Application |
Online Access: | https://doi.org/10.1177/2397847318759327 |
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