Small airway dysfunction as predictor and marker for clinical response to biological therapy in severe eosinophilic asthma: a longitudinal observational study

Small airway dysfunction as predictor and marker for clinical response to biological therapy in severe eosinophilic asthma: a longitudinal observational study

Abstract Background Anti-T2 biological therapies have proven to effectively reduce acute exacerbations and daily doses of oral steroids in severe eosinophilic asthma. Despite the remarkable clinical efficacy, there are usually only moderate improvements in airflow limitation, suggesting that other m...

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Bibliographic Details
Main Authors: Mustafa Abdo, Henrik Watz, Vera Veith, Anne-Marie Kirsten, Heike Biller, Frauke Pedersen, Erika von Mutius, Matthias V. Kopp, Gesine Hansen, Benjamin Waschki, Klaus F. Rabe, Frederik Trinkmann, Thomas Bahmer
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Respiratory Research
Subjects:
Anti-T2 biologics
Asthma control
Small airways dysfunction
FEV1
Online Access:http://link.springer.com/article/10.1186/s12931-020-01543-5

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