A temporal model of human IgE and IgG antibody function

The diversity of the human antibody repertoire that is generated by V(D)J gene rearrangement is extended by nine constant region genes that give antibodies their complex array of effector functions. The application of high throughput sequencing to the study of V(D)J gene rearrangements has led to si...

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Bibliographic Details
Main Authors: Andrew M Collins, Katherine J. L. Jackson
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Immunology
Subjects:
IgE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00235/full