Automated ensemble modeling with modelMaGe: analyzing feedback mechanisms in the Sho1 branch of the HOG pathway.
In systems biology uncertainty about biological processes translates into alternative mathematical model candidates. Here, the goal is to generate, fit and discriminate several candidate models that represent different hypotheses for feedback mechanisms responsible for downregulating the response of...
Main Authors: | Jörg Schaber, Max Flöttmann, Jian Li, Carl-Fredrik Tiger, Stefan Hohmann, Edda Klipp |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3068199?pdf=render |
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