Antibody to mCLCA3 suppresses symptoms in a mouse model of asthma.
BACKGROUND:Asthma is a complex and heterogeneous chronic inflammatory disorder that is associated with mucous cell metaplasia and mucus hypersecretion. Functional genomic analysis indicates that mucous cell metaplasia and mucus hypersecretion depend on members of the calcium-activated chloride chann...
Main Authors: | Liqiang Song, Dapeng Liu, Changgui Wu, Shouzhen Wu, Junlan Yang, Fangping Ren, Yan Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3857274?pdf=render |
Similar Items
-
The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses.
by: Kimberly L Jordan-Williams, et al.
Published: (2016-01-01) -
mCLCA3 modulates IL-17 and CXCL-1 induction and leukocyte recruitment in murine Staphylococcus aureus pneumonia.
by: Kristina Dietert, et al.
Published: (2014-01-01) -
The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.
by: Nancy A Erickson, et al.
Published: (2015-01-01) -
The role of hCLCA2 and hCLCA4 in suppression of breast cancer progression
by: Yu, Yang
Published: (2014) -
CLCA : chloride channel or modulator?
by: Loewen, Matthew Eric
Published: (2004)