Graft Versus Host Disease Associated with Immune Checkpoint Inhibitors: A Pharmacovigilance Study and Systematic Literature Review

Graft Versus Host Disease Associated with Immune Checkpoint Inhibitors: A Pharmacovigilance Study and Systematic Literature Review

Background: In patients with allogenic hematopoietic stem cell transplantation (allo-HSCT), immune-checkpoint inhibitors (ICI) are used to treat malignancy recurrence. However, ICI are also associated with graft vs. host disease (GVHD). In this pharmacovigilance analysis, we aimed to characterize ca...

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Bibliographic Details
Main Authors: Lee S. Nguyen, Lisa Raia, Bénédicte Lebrun-Vignes, Joe-Elie Salem
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
immunotherapy
pharmacovigilance
vigibase®
graft-versus-host disease
adverse (side) effects
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.619649/full

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