Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.

Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.

Our results confirmed the more aggressive behavior of PSRCC compared to MBC. This tumor is frequently associated with more frequent lymphatic metastasis, higher Ki67 labeling index, more advanced stage disease as well as simultaneous vimentin upregulation and E-cadherin downregulation. Different man...

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Main Authors: Xiufeng Wu, Zhenzhen Zhang, Xin Li, Qingzhong Lin, Gang Chen, Jianping Lu, Yi Zeng, Dan Hu, Kai Huang, Zhiwu Lin, Jun Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5008818?pdf=render
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spelling doaj-d361e950315848ceb2e78170cb995f772020-11-25T02:29:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01119e016208810.1371/journal.pone.0162088Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.Xiufeng WuZhenzhen ZhangXin LiQingzhong LinGang ChenJianping LuYi ZengDan HuKai HuangZhiwu LinJun YanOur results confirmed the more aggressive behavior of PSRCC compared to MBC. This tumor is frequently associated with more frequent lymphatic metastasis, higher Ki67 labeling index, more advanced stage disease as well as simultaneous vimentin upregulation and E-cadherin downregulation. Different management guidelines should be considered for the two types.http://europepmc.org/articles/PMC5008818?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Xiufeng Wu
Zhenzhen Zhang
Xin Li
Qingzhong Lin
Gang Chen
Jianping Lu
Yi Zeng
Dan Hu
Kai Huang
Zhiwu Lin
Jun Yan
spellingShingle Xiufeng Wu
Zhenzhen Zhang
Xin Li
Qingzhong Lin
Gang Chen
Jianping Lu
Yi Zeng
Dan Hu
Kai Huang
Zhiwu Lin
Jun Yan
Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
PLoS ONE
author_facet Xiufeng Wu
Zhenzhen Zhang
Xin Li
Qingzhong Lin
Gang Chen
Jianping Lu
Yi Zeng
Dan Hu
Kai Huang
Zhiwu Lin
Jun Yan
author_sort Xiufeng Wu
title Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
title_short Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
title_full Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
title_fullStr Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
title_full_unstemmed Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
title_sort poorer prognosis of primary signet-ring cell carcinoma of the breast compared with mucinous carcinoma.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2016-01-01
description Our results confirmed the more aggressive behavior of PSRCC compared to MBC. This tumor is frequently associated with more frequent lymphatic metastasis, higher Ki67 labeling index, more advanced stage disease as well as simultaneous vimentin upregulation and E-cadherin downregulation. Different management guidelines should be considered for the two types.
url http://europepmc.org/articles/PMC5008818?pdf=render
work_keys_str_mv AT xiufengwu poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT zhenzhenzhang poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT xinli poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT qingzhonglin poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT gangchen poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT jianpinglu poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT yizeng poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT danhu poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT kaihuang poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT zhiwulin poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
AT junyan poorerprognosisofprimarysignetringcellcarcinomaofthebreastcomparedwithmucinouscarcinoma
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