White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies
The association of meat consumption with mortality and morbidity for non-communicable diseases has been extensively studied. However, the relation of white meat consumption with health outcomes remains controversial. The present meta-analysis was conducted to comprehensively analyze the available ev...
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doaj-d376b7e337c947b6816ce589d137d1092021-02-21T00:03:23ZengMDPI AGNutrients2072-66432021-02-011367667610.3390/nu13020676White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort StudiesRoberta Lupoli0Marilena Vitale1Ilaria Calabrese2Annalisa Giosuè3Gabriele Riccardi4Olga Vaccaro5Department of Clinical Medicine and Surgery, “Federico II” University, 80131 Naples, ItalyDepartment of Clinical Medicine and Surgery, “Federico II” University, 80131 Naples, ItalyDepartment of Clinical Medicine and Surgery, “Federico II” University, 80131 Naples, ItalyDepartment of Clinical Medicine and Surgery, “Federico II” University, 80131 Naples, ItalyDepartment of Clinical Medicine and Surgery, “Federico II” University, 80131 Naples, ItalyDepartment of Pharmacy, “Federico II” University, 80131 Naples, ItalyThe association of meat consumption with mortality and morbidity for non-communicable diseases has been extensively studied. However, the relation of white meat consumption with health outcomes remains controversial. The present meta-analysis was conducted to comprehensively analyze the available evidence on the consistency and strength of the association between the consumption of white meat, death from any cause and incidence of fatal and non-fatal cardiovascular (CV) events. PubMed, Web of Science, Scopus and Embase databases were searched for articles published up to April 30, 2020. We included prospective cohort studies reporting relative risks and pertinent 95% confidence intervals (CI) for all-cause mortality and/or CV events (fatal or non-fatal). A total of 22 studies were included in the meta-analysis. Eleven studies (14 data sets) reported data on all-cause mortality, 10 studies (15 datasets) on cardiovascular disease (CVD) mortality and 10 studies (11 datasets) on non-fatal CV events. When comparing the highest versus the lowest consumption of white meat, the pooled OR and pertinent 95% CI were 0.94 (0.90, 0.97, <i>p</i> < 0.001) for all-cause mortality, 0.95 (0.89, 1.01, <i>p </i>= 0.13) for CV mortality, and 0.99 (0.95, 1.02, <i>p</i> = 0.48) for non-fatal CV events. In conclusion, the study shows for the first time a robust and inverse association between white meat consumption and all-cause mortality and a neutral association with CV mortality and morbidity. This highlights the importance of differentiating the meat types for what concerns their health effects and suggests that white meat might be a healthier alternative to read and processed meat consumption.https://www.mdpi.com/2072-6643/13/2/676meta-analysiscohort studieswhite meatpoultryall-cause mortalitycardiovascular disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Roberta Lupoli Marilena Vitale Ilaria Calabrese Annalisa Giosuè Gabriele Riccardi Olga Vaccaro |
spellingShingle |
Roberta Lupoli Marilena Vitale Ilaria Calabrese Annalisa Giosuè Gabriele Riccardi Olga Vaccaro White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies Nutrients meta-analysis cohort studies white meat poultry all-cause mortality cardiovascular disease |
author_facet |
Roberta Lupoli Marilena Vitale Ilaria Calabrese Annalisa Giosuè Gabriele Riccardi Olga Vaccaro |
author_sort |
Roberta Lupoli |
title |
White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies |
title_short |
White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies |
title_full |
White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies |
title_fullStr |
White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies |
title_full_unstemmed |
White Meat Consumption, All-Cause Mortality, and Cardiovascular Events: A Meta-Analysis of Prospective Cohort Studies |
title_sort |
white meat consumption, all-cause mortality, and cardiovascular events: a meta-analysis of prospective cohort studies |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2021-02-01 |
description |
The association of meat consumption with mortality and morbidity for non-communicable diseases has been extensively studied. However, the relation of white meat consumption with health outcomes remains controversial. The present meta-analysis was conducted to comprehensively analyze the available evidence on the consistency and strength of the association between the consumption of white meat, death from any cause and incidence of fatal and non-fatal cardiovascular (CV) events. PubMed, Web of Science, Scopus and Embase databases were searched for articles published up to April 30, 2020. We included prospective cohort studies reporting relative risks and pertinent 95% confidence intervals (CI) for all-cause mortality and/or CV events (fatal or non-fatal). A total of 22 studies were included in the meta-analysis. Eleven studies (14 data sets) reported data on all-cause mortality, 10 studies (15 datasets) on cardiovascular disease (CVD) mortality and 10 studies (11 datasets) on non-fatal CV events. When comparing the highest versus the lowest consumption of white meat, the pooled OR and pertinent 95% CI were 0.94 (0.90, 0.97, <i>p</i> < 0.001) for all-cause mortality, 0.95 (0.89, 1.01, <i>p </i>= 0.13) for CV mortality, and 0.99 (0.95, 1.02, <i>p</i> = 0.48) for non-fatal CV events. In conclusion, the study shows for the first time a robust and inverse association between white meat consumption and all-cause mortality and a neutral association with CV mortality and morbidity. This highlights the importance of differentiating the meat types for what concerns their health effects and suggests that white meat might be a healthier alternative to read and processed meat consumption. |
topic |
meta-analysis cohort studies white meat poultry all-cause mortality cardiovascular disease |
url |
https://www.mdpi.com/2072-6643/13/2/676 |
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