Isoniazid, pyrazinamide and rifampicin content variation in split fixed-dose combination tablets.

Isoniazid, pyrazinamide and rifampicin content variation in split fixed-dose combination tablets.

In most developing countries, paediatric tuberculosis is treated with split tablets leading to potential inaccuracy in the dose delivery and drug exposure. There is no data on the quality of first-line drugs content in split fixed-dose combination tablets.To determine Isoniazid, Pyrazinamide and Rif...

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Bibliographic Details
Main Authors: Thomas Pouplin, Pham Nguyen Phuong, Pham Van Toi, Julie Nguyen Pouplin, Jeremy Farrar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4086978?pdf=render

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