The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells.
The mechanisms underlying adenovirus-mediated autophagy are currently unknown. Recently, members of the Bcl-2 protein family have been associated with autophagy. It was also reported that the Bcl-2 homology-3 (BH3) domain encompassed by both Beclin 1 and Bcl-2-like proteins is essential for their pr...
Main Authors: | Sujan Piya, Erin J White, Sarah R Klein, Hong Jiang, Timothy J McDonnell, Candelaria Gomez-Manzano, Juan Fueyo |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3248451?pdf=render |
Similar Items
-
The Role of Beclin 1-Dependent Autophagy in Cancer
by: Silvia Vega-Rubín-de-Celis
Published: (2019-12-01) -
Beclin 1 Phosphorylation – at the Center of Autophagy Regulation
by: Manoj B. Menon, et al.
Published: (2018-10-01) -
Autophagy-Related Beclin 1 and Head and Neck Cancers
by: Hu YJ, et al.
Published: (2020-06-01) -
Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens.
by: Sarah R Klein, et al.
Published: (2016-01-01) -
Regulation of Beclin 1-Mediated Autophagy by Oncogenic Tyrosine Kinases
by: Silvia Vega-Rubín-de-Celis, et al.
Published: (2020-12-01)