Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice.
Previous studies have shown that proteasome inhibition can have beneficial effects in dystrophic mouse models. In this study, we have investigated the effects of a new selective proteasome inhibitor, CLi, a strong caspase-like inhibitor of the 20S proteasome, on skeletal and cardiac muscle functions...
Main Authors: | Yeranuhi Hovhannisyan, Gagik Melikyan, Nathalie Mougenot, Jacqueline Gao-Li, Bertrand Friguet, Denise Paulin, Zhenlin Li, Arnaud Ferry, Onnik Agbulut |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0215821 |
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