Glutamine treatment attenuates endoplasmic reticulum stress and apoptosis in TNBS-induced colitis.

Endoplasmic reticulum (ER) stress and apoptotic cell death play an important role in the pathogenesis and perpetuation of inflammatory bowel disease (IBD). We aimed to explore the potential of glutamine to reduce ER stress and apoptosis in a rat model of experimental IBD. Colitis was induced in male...

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Bibliographic Details
Main Authors: Irene Crespo, Beatriz San-Miguel, Carolina Prause, Norma Marroni, María J Cuevas, Javier González-Gallego, María J Tuñón
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209735/pdf/?tool=EBI