Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G.
Protease-mediated degradation of proteins is critical in a plethora of physiological processes. Neutrophils secrete serine proteases including cathepsin G (CatG), neutrophile elastase (NE), and proteinase 3 (PR3) together with lactoferrin (LF) as a first cellular immune response against pathogens. H...
Main Authors: | Steffen Eipper, Robin Steiner, Adam Lesner, Marcin Sienczyk, David Palesch, Marc-Eric Halatsch, Ewa Zaczynska, Christopher Heim, Marcus D Hartmann, Michal Zimecki, Christian Rainer Wirtz, Timo Burster |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4795699?pdf=render |
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