Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience
The aim of this study was to analyze the values of biochemical parameters in patients with diabetic ketoacidosis and ketonuria. In this prospective comparative study conducted at the Clinical Center of the University of Sarajevo, hundred patients of both genders with diabetes mellitus were enrolled....
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doaj-d3d70c685ead4abaae124aaac9184ee72020-11-25T02:27:50ZengSciendoActa Facultatis Medicae Naissensis2217-25212018-06-0135213213910.2478/afmnai-2018-0015afmnai-2018-0015Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina ExperienceHasković Edhem0Bureković Azra1Husić Adnan2Fočak Muhamed3Islamagić Erna4Faculty of Science, University of Sarajevo,Sarajevo, Bosnia and HerzegovinaClinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of the University of Sarajevo,Sarajevo, Bosnia and HerzegovinaFaculty of Science, University of Sarajevo,Sarajevo, Bosnia and HerzegovinaFaculty of Science, University of Sarajevo,Sarajevo, Bosnia and HerzegovinaFaculty of Science, University of Sarajevo,Sarajevo, Bosnia and HerzegovinaThe aim of this study was to analyze the values of biochemical parameters in patients with diabetic ketoacidosis and ketonuria. In this prospective comparative study conducted at the Clinical Center of the University of Sarajevo, hundred patients of both genders with diabetes mellitus were enrolled. Newly diagnosed diabetic patients with complications like acute ketoacidosis (n = 50) and ketonuria (n = 50) were included in this study and compared. The values of biochemical parameters in these patients were analyzed. We found that mean values of pH, base excess, hydrogencarbonate, sodium, glucose, urea and creatinine concentrations in patients with ketoacidosis were significantly different compared to patients with ketonuria. The values of potassium and calcium serum concentrations were not significantly different. Also, values of pH, base excess, as well as concentrations of hydrogencarbonate, sodium, potassium, calcium, glucose, urea and creatinine were not significantly different between male and female patients with diabetic ketoacidosis. In patients with diabetic ketonuria we found a correlation between admission glucose concentration and acid-base balance.http://www.degruyter.com/view/j/afmnai.2018.35.issue-2/afmnai-2018-0015/afmnai-2018-0015.xml?format=INTketoacidosisdiabetes mellitusketonuria |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hasković Edhem Bureković Azra Husić Adnan Fočak Muhamed Islamagić Erna |
spellingShingle |
Hasković Edhem Bureković Azra Husić Adnan Fočak Muhamed Islamagić Erna Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience Acta Facultatis Medicae Naissensis ketoacidosis diabetes mellitus ketonuria |
author_facet |
Hasković Edhem Bureković Azra Husić Adnan Fočak Muhamed Islamagić Erna |
author_sort |
Hasković Edhem |
title |
Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience |
title_short |
Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience |
title_full |
Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience |
title_fullStr |
Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience |
title_full_unstemmed |
Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience |
title_sort |
acid-base status of patients with diabetic ketoacidosis and ketonuria: bosnia and herzegovina experience |
publisher |
Sciendo |
series |
Acta Facultatis Medicae Naissensis |
issn |
2217-2521 |
publishDate |
2018-06-01 |
description |
The aim of this study was to analyze the values of biochemical parameters in patients with diabetic ketoacidosis and ketonuria. In this prospective comparative study conducted at the Clinical Center of the University of Sarajevo, hundred patients of both genders with diabetes mellitus were enrolled. Newly diagnosed diabetic patients with complications like acute ketoacidosis (n = 50) and ketonuria (n = 50) were included in this study and compared. The values of biochemical parameters in these patients were analyzed. We found that mean values of pH, base excess, hydrogencarbonate, sodium, glucose, urea and creatinine concentrations in patients with ketoacidosis were significantly different compared to patients with ketonuria. The values of potassium and calcium serum concentrations were not significantly different. Also, values of pH, base excess, as well as concentrations of hydrogencarbonate, sodium, potassium, calcium, glucose, urea and creatinine were not significantly different between male and female patients with diabetic ketoacidosis. In patients with diabetic ketonuria we found a correlation between admission glucose concentration and acid-base balance. |
topic |
ketoacidosis diabetes mellitus ketonuria |
url |
http://www.degruyter.com/view/j/afmnai.2018.35.issue-2/afmnai-2018-0015/afmnai-2018-0015.xml?format=INT |
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