Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer

Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer

Population-specific profiling of mutations in cancer genes is of critical importance for the understanding of cancer biology in general as well as the establishment of optimal diagnostics and treatment guidelines for that particular population. Although genetic analysis of tumor tissue is often used...

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Main Authors: Le Son Tran, Quynh-Tho Thi Nguyen, Chu Van Nguyen, Vu-Uyen Tran, Thai-Hoa Thi Nguyen, Ha Thu Le, Mai-Lan Thi Nguyen, Vu Thuong Le, Lam-Son Pham, Binh Thanh Vo, Anh-Thu Huynh Dang, Luan Thanh Nguyen, Thien-Chi Van Nguyen, Hong-Anh Thi Pham, Thanh-Truong Tran, Long Hung Nguyen, Thanh-Thanh Thi Nguyen, Kim-Huong Thi Nguyen, Yen-Vi Vu, Nguyen Huu Nguyen, Vinh-Quang Bui, Hai-Ha Bui, Thanh-Thuy Thi Do, Nien Vinh Lam, Kiet Truong Dinh, Minh-Duy Phan, Hoai-Nghia Nguyen, Hoa Giang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
liquid biopsy
circulating tumor DNA
non-small cell lung cancer
actionable mutations
ultra-deep sequencing
tissue biopsy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01351/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01351/full

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