NF-κBp65 and Expression of Its Pro-Inflammatory Target Genes Are Upregulated in the Subcutaneous Adipose Tissue of Cachectic Cancer Patients

NF-κBp65 and Expression of Its Pro-Inflammatory Target Genes Are Upregulated in the Subcutaneous Adipose Tissue of Cachectic Cancer Patients

Cancer cachexia, of which the most notable symptom is severe and rapid weight loss, is present in the majority of patients with advanced cancer. Inflammatory mediators play an important role in the development of cachexia, envisaged as a chronic inflammatory syndrome. The white adipose tissue (WAT)...

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Bibliographic Details
Main Authors: Rodolfo Gonzalez Camargo, Daniela Mendes dos Reis Riccardi, Henrique Quintas Teixeira Ribeiro, Luiz Carlos Carnevali, Emidio Marques de Matos-Neto, Lucas Enjiu, Rodrigo Xavier Neves, Joanna Darck Carola Correia Lima, Raquel Galvão Figuerêdo, Paulo Sérgio Martins de Alcântara, Linda Maximiano, José Otoch, Miguel Luiz Batista, Gerhard Püschel, Marilia Seelaender
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Nutrients
Subjects:
cancer cachexia
inflammation
white adipose tissue
NF-κB
IκB
Online Access:http://www.mdpi.com/2072-6643/7/6/4465

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