HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER

The paper is devoted to the study of the expression of markers associated with invasive breast carcinoma. The study included a surgical material from 107 patients with invasive carcinoma of the non-specific type of breast cancer who had not previously received neoadjuvant therapy. The study revealed...

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Bibliographic Details
Main Authors: N. V. Krakhmal, M. V. Zavyalova, V. M. Perelmuter, S. V. Vtorushin, E. M. Slonimskaya, E. V. Denisov
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-10-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
Online Access:https://www.siboncoj.ru/jour/article/view/387
Description
Summary:The paper is devoted to the study of the expression of markers associated with invasive breast carcinoma. The study included a surgical material from 107 patients with invasive carcinoma of the non-specific type of breast cancer who had not previously received neoadjuvant therapy. The study revealed a number of markers related to invasive tumor growth, characterized by a pronounced heterogeneous expression pattern in all cases. Study of the expression of markers associated with invasive breast carcinoma showed that not all cells are able to promote invasive growth in different periods of time, but the fact of detecting the positive expression of the markers in tissue tumors indicates a more aggressive cancer phenotype with a high potential for invasion.
ISSN:1814-4861
2312-3168