HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER

HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER

The paper is devoted to the study of the expression of markers associated with invasive breast carcinoma. The study included a surgical material from 107 patients with invasive carcinoma of the non-specific type of breast cancer who had not previously received neoadjuvant therapy. The study revealed...

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Main Authors: N. V. Krakhmal, M. V. Zavyalova, V. M. Perelmuter, S. V. Vtorushin, E. M. Slonimskaya, E. V. Denisov
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-10-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
heterogeneous expression
invasion
breast cancer
Online Access:https://www.siboncoj.ru/jour/article/view/387
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spelling doaj-d3dde2f0a86340868a99022c528794662021-07-28T21:02:02ZrusTomsk National Research Medical Center of the Russian Academy of SciencesSibirskij Onkologičeskij Žurnal1814-48612312-31682016-10-01154566110.21294/1814-4861-2016-15-4-56-61361HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCERN. V. Krakhmal0M. V. Zavyalova1V. M. Perelmuter2S. V. Vtorushin3E. M. Slonimskaya4E. V. Denisov5Siberian State Medical University, TomskSiberian State Medical University, Tomsk; Tomsk Cancer Research Institute, Tomsk; Tomsk State University, TomskSiberian State Medical University, Tomsk; Tomsk Cancer Research Institute, TomskSiberian State Medical University, Tomsk; Tomsk Cancer Research Institute, TomskSiberian State Medical University, Tomsk; Tomsk Cancer Research Institute, TomskTomsk Cancer Research Institute, Tomsk; Tomsk State University, TomskThe paper is devoted to the study of the expression of markers associated with invasive breast carcinoma. The study included a surgical material from 107 patients with invasive carcinoma of the non-specific type of breast cancer who had not previously received neoadjuvant therapy. The study revealed a number of markers related to invasive tumor growth, characterized by a pronounced heterogeneous expression pattern in all cases. Study of the expression of markers associated with invasive breast carcinoma showed that not all cells are able to promote invasive growth in different periods of time, but the fact of detecting the positive expression of the markers in tissue tumors indicates a more aggressive cancer phenotype with a high potential for invasion.https://www.siboncoj.ru/jour/article/view/387heterogeneous expressioninvasionbreast cancer
collection DOAJ
language Russian
format Article
sources DOAJ
author N. V. Krakhmal
M. V. Zavyalova
V. M. Perelmuter
S. V. Vtorushin
E. M. Slonimskaya
E. V. Denisov
spellingShingle N. V. Krakhmal
M. V. Zavyalova
V. M. Perelmuter
S. V. Vtorushin
E. M. Slonimskaya
E. V. Denisov
HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER
Sibirskij Onkologičeskij Žurnal
heterogeneous expression
invasion
breast cancer
author_facet N. V. Krakhmal
M. V. Zavyalova
V. M. Perelmuter
S. V. Vtorushin
E. M. Slonimskaya
E. V. Denisov
author_sort N. V. Krakhmal
title HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER
title_short HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER
title_full HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER
title_fullStr HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER
title_full_unstemmed HETEROGENENOUS EXPRESSION OF MARKERS ASSOCIATED WITN INVASIVE BREAST CANCER
title_sort heterogenenous expression of markers associated witn invasive breast cancer
publisher Tomsk National Research Medical Center of the Russian Academy of Sciences
series Sibirskij Onkologičeskij Žurnal
issn 1814-4861
2312-3168
publishDate 2016-10-01
description The paper is devoted to the study of the expression of markers associated with invasive breast carcinoma. The study included a surgical material from 107 patients with invasive carcinoma of the non-specific type of breast cancer who had not previously received neoadjuvant therapy. The study revealed a number of markers related to invasive tumor growth, characterized by a pronounced heterogeneous expression pattern in all cases. Study of the expression of markers associated with invasive breast carcinoma showed that not all cells are able to promote invasive growth in different periods of time, but the fact of detecting the positive expression of the markers in tissue tumors indicates a more aggressive cancer phenotype with a high potential for invasion.
topic heterogeneous expression
invasion
breast cancer
url https://www.siboncoj.ru/jour/article/view/387
work_keys_str_mv AT nvkrakhmal heterogenenousexpressionofmarkersassociatedwitninvasivebreastcancer
AT mvzavyalova heterogenenousexpressionofmarkersassociatedwitninvasivebreastcancer
AT vmperelmuter heterogenenousexpressionofmarkersassociatedwitninvasivebreastcancer
AT svvtorushin heterogenenousexpressionofmarkersassociatedwitninvasivebreastcancer
AT emslonimskaya heterogenenousexpressionofmarkersassociatedwitninvasivebreastcancer
AT evdenisov heterogenenousexpressionofmarkersassociatedwitninvasivebreastcancer
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