Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study

Ameliorative role of SIRT1 in peritoneal fibrosis: an in vivo and in vitro study

Abstract Background Peritoneal fibrosis is one of the major complications induced by peritoneal dialysis (PD). Damaged integrity and function of peritoneum caused by peritoneal fibrosis not only limits the curative efficacy of PD and but affects the prognosis of patients. However, the detailed mecha...

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Bibliographic Details
Main Authors: Yanhong Guo, Liuwei Wang, Rong Gou, Yulin Wang, Xiujie Shi, Yage Zhang, Xinxin Pang, Lin Tang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cell & Bioscience
Subjects:
Peritoneal fibrosis
Peritoneum
SIRT1
TGF‐β
Mesothelial-mesenchymal transition
Online Access:https://doi.org/10.1186/s13578-021-00591-8

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