Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) as the predictor of neonatal mortality hospitalized in neonatal intensive care unit

• Main Authors: James Thimoty, Dany Hilmanto, Tetty Yuniati
• Format: Article
• Language: English
• Published: Indonesian Pediatric Society Publishing House 2009-07-01
• Series: Paediatrica Indonesiana
• Subjects: SNAPPE II; mortality; NICU
• Online Access: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/544
• ISSN: 0030-9311; 2338-476X

Background The assesment of severity of illness with scoring system has been used to predict neonatal mortality in neonatal intensive care unit (NICU). Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) is the best scoring system although most of the studies were commonly conducted in developed countries. Objective To evaluate SNAPPE II as the predictor of neonatal mortality in NICU Hasan Sadikin General Hospital (HSGH) Ban dung. Methods This was a longitudinal observational study. All neonates hospitalized in NICU HSGH during the period of August to November 2008 were investigated according to SNAPPE II requirements. We excluded subjects admitted more than 48 hours of age, who were discharged or moved to intermediate newborn care ward less than 24 hours after admission. Prediction of mortality and determination of SNAPPE II cut-off point were analyzed using logistic regression. Discrimination was analyzed using receiver operating characteristic (ROC) and calibration was analyzed using Hosmer-Lemeshow goodness-of-fit. Results Forty subjects fulfilled the inclusion criteria. There was a good relation between SNAPPE II and mortality prediction (P = 0.007). The cut-off point for predicting mortality was 51. SNAPPE II showed good discrimination with AUC 0.933 (95% CI 0.843 to 1.0) and good calibration 1.69 (P = 0.97). Conclusion SNAPPE II can be used to predict neonatal mortality in NICU similar to that found in developed countries.