The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization.
Translocation to the nucleus of diacylglycerol kinase (DGK)- ζ is dependent on a sequence homologous to the effector domain of Myristoylated Alanine Rich C-Kinase Substrate (MARCKS). These data would suggest that MARCKS could also localize to the nucleus. A single report demonstrated immunofluoresce...
Main Authors: | Timothy D Rohrbach, Nishi Shah, William P Jackson, Erin V Feeney, Samantha Scanlon, Robert Gish, Ryan Khodadadi, Stephen O Hyde, Patricia H Hicks, Joshua C Anderson, John S Jarboe, Christopher D Willey |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4607481?pdf=render |
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