Electrophysiological study of nerves in type-II reaction in leprosy
Background: Leprosy is a chronic granulomatous infection primarily affecting the peripheral nervous system, skin and reticuloendothelial system. Cutaneous nerves are severely affected in lepra reaction and this leads to morbidity. Objective: To study electrophysiological pattern of different nerves...
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Wolters Kluwer Medknow Publications
2017-01-01
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doaj-d4025ba5fff34c838ed16cf46976d6c02020-11-24T23:27:05ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112017-01-0162653654010.4103/ijd.IJD_38_17Electrophysiological study of nerves in type-II reaction in leprosySantosh Kumar SinghSunil Kumar GuptaR D MukhijaA K ThackerBackground: Leprosy is a chronic granulomatous infection primarily affecting the peripheral nervous system, skin and reticuloendothelial system. Cutaneous nerves are severely affected in lepra reaction and this leads to morbidity. Objective: To study electrophysiological pattern of different nerves involved in Type-II reactions in leprosy. Method: The present study was undertaken in 21 leprosy patients with Type-II reactions attending in and out-patient department of Dermatology & Venereology, B.R.D. Medical College, Gorakhpur from July 2005 to October 2006. This was a prospective case control study in which 20 healthy, age and sex matched people with no evidence of any disease (particularly nerve involvement) were included. Limitation: Lesser number of cases were studied. Result: The proximal motor conduction latency was significantly prolonged in both ulnar and common peroneal nerve and proximal motor conduction velocity was also significantly reduced. On examining the values beyond 2S.D. of the control value, distal latency was not affected and only proximal conduction was affected in ulnar nerve. Conclusion: In Type II lepra reaction the motor conduction abnormalities are not prominent. Abnormalities are relatively more marked in the proximal segment.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=6;spage=536;epage=540;aulast=SinghDistal latencyerythema nodosum leprosumleprosyproximal motor conduction velocityType-II lepra reaction |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Santosh Kumar Singh Sunil Kumar Gupta R D Mukhija A K Thacker |
spellingShingle |
Santosh Kumar Singh Sunil Kumar Gupta R D Mukhija A K Thacker Electrophysiological study of nerves in type-II reaction in leprosy Indian Journal of Dermatology Distal latency erythema nodosum leprosum leprosy proximal motor conduction velocity Type-II lepra reaction |
author_facet |
Santosh Kumar Singh Sunil Kumar Gupta R D Mukhija A K Thacker |
author_sort |
Santosh Kumar Singh |
title |
Electrophysiological study of nerves in type-II reaction in leprosy |
title_short |
Electrophysiological study of nerves in type-II reaction in leprosy |
title_full |
Electrophysiological study of nerves in type-II reaction in leprosy |
title_fullStr |
Electrophysiological study of nerves in type-II reaction in leprosy |
title_full_unstemmed |
Electrophysiological study of nerves in type-II reaction in leprosy |
title_sort |
electrophysiological study of nerves in type-ii reaction in leprosy |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Dermatology |
issn |
0019-5154 1998-3611 |
publishDate |
2017-01-01 |
description |
Background: Leprosy is a chronic granulomatous infection primarily affecting the peripheral nervous system, skin and reticuloendothelial system. Cutaneous nerves are severely affected in lepra reaction and this leads to morbidity. Objective: To study electrophysiological pattern of different nerves involved in Type-II reactions in leprosy. Method: The present study was undertaken in 21 leprosy patients with Type-II reactions attending in and out-patient department of Dermatology & Venereology, B.R.D. Medical College, Gorakhpur from July 2005 to October 2006. This was a prospective case control study in which 20 healthy, age and sex matched people with no evidence of any disease (particularly nerve involvement) were included. Limitation: Lesser number of cases were studied. Result: The proximal motor conduction latency was significantly prolonged in both ulnar and common peroneal nerve and proximal motor conduction velocity was also significantly reduced. On examining the values beyond 2S.D. of the control value, distal latency was not affected and only proximal conduction was affected in ulnar nerve. Conclusion: In Type II lepra reaction the motor conduction abnormalities are not prominent. Abnormalities are relatively more marked in the proximal segment. |
topic |
Distal latency erythema nodosum leprosum leprosy proximal motor conduction velocity Type-II lepra reaction |
url |
http://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=6;spage=536;epage=540;aulast=Singh |
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