Development of a PCR algorithm to detect and characterize Neisseria meningitidis carriage isolates in the African meningitis belt.

Development of a PCR algorithm to detect and characterize Neisseria meningitidis carriage isolates in the African meningitis belt.

Improved methods for the detection and characterization of carried Neisseria meningitidis isolates are needed. We evaluated a multiplex PCR algorithm for the detection of a variety of carriage strains in the meningitis belt. To further improve the sensitivity and specificity of the existing PCR assa...

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Bibliographic Details
Main Authors: Kanny Diallo, Mamadou D Coulibaly, Lisa S Rebbetts, Odile B Harrison, Jay Lucidarme, Kadidja Gamougam, Yenenesh K Tekletsion, Akalifa Bugri, Aliou Toure, Bassira Issaka, Marietou Dieng, Caroline Trotter, Jean-Marc Collard, Samba O Sow, Xin Wang, Leonard W Mayer, Ray Borrow, Brian M Greenwood, Martin C J Maiden, Olivier Manigart, MenAfriCar Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0206453

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