Diurnal Variation in Peak Expiratory Flow and Forced Expiratory Volume
Introduction: Diurnal variability in airways has most commonly been reported using peak expiratory flow (PEF) and forced expiratory volume in one second (FEV1). Characteristics of variability in small, mid and large airways caliber are expected to be different but have not been studied. Aim: Th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6661/15156_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdf |
| Summary: | Introduction: Diurnal variability in airways has most commonly
been reported using peak expiratory flow (PEF) and forced
expiratory volume in one second (FEV1). Characteristics of
variability in small, mid and large airways caliber are expected to
be different but have not been studied.
Aim: The aim of the study was to assess diurnal variation in small
mid and large airways caliber using FEF25, FEF50, FEF75 and
FEF25-75 along with PEF and FEV1 in healthy subjects.
Materials and Methods: Spirometry was performed in 161
healthy subjects twice in a day. Diurnal variability in FEF25,
FEF50, FEF75, FEF25-75, PEF and FEV1 were determined and
compared.
Results: It revealed that all parameters exhibit significant diurnal
variability. Diurnal variability is highest in large airways and lowest
in smaller airways.
Conclusion: Proximal airways show greater diurnal variation in
their caliber than distal airways as reflected by greater variability in
PEF as compared to FEV1. |
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| ISSN: | 2249-782X 0973-709X |