Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015
Abstract Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013–2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. N...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-06987-2 |
id |
doaj-d41cd8a82aec41aaae445884a231b5fa |
---|---|
record_format |
Article |
spelling |
doaj-d41cd8a82aec41aaae445884a231b5fa2020-12-08T00:28:09ZengNature Publishing GroupScientific Reports2045-23222017-07-017111110.1038/s41598-017-06987-2Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015Keyu Feng0Feng Wang1Yu Xue2Qingfeng Zhou3Feng Chen4Yingzuo Bi5Qingmei Xie6College of Animal Science, South China Agricultural UniversityGuangdong Wen’s Foodstuff Group Co. LTD., Guangdong Enterprise Key Laboratory for Animal Health and Environmental ControlGuangdong Wen’s Foodstuff Group Co. LTD., Guangdong Enterprise Key Laboratory for Animal Health and Environmental ControlGuangdong Wen’s Foodstuff Group Co. LTD., Guangdong Enterprise Key Laboratory for Animal Health and Environmental ControlCollege of Animal Science, South China Agricultural UniversityCollege of Animal Science, South China Agricultural UniversityCollege of Animal Science, South China Agricultural UniversityAbstract Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013–2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. Nucleotide homologies ranged from 63.1–99.9% and amino acid homologies ranging from 60.2–100%. At least seven IBV genotypes were co-circulating in commercial chicken farms in southern China. The IBV isolates were genetically diverse and underwent continuing evolution. The QX-type, TW I-type, and 4/91-type were the most common genotypes during the three-year observation period and accounted for 88.8% of the isolated strains. Notably, the prevalence of the TW I-type strains has been increasing in recent years and has become the most common genotype in China. The emergence of variant IBV strains can be attributed to recombination. Serologic analysis and antigenic 3D cartography of 4 reference and 14 field isolated strains indicated the surveyed IBVs had diverse serology types and that the serotype of the isolated QX-type and TW I-type strains was distinct from the vaccines strains. Therefore, long-term continuing surveillance is necessary for IBV prevention and control.https://doi.org/10.1038/s41598-017-06987-2 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Keyu Feng Feng Wang Yu Xue Qingfeng Zhou Feng Chen Yingzuo Bi Qingmei Xie |
spellingShingle |
Keyu Feng Feng Wang Yu Xue Qingfeng Zhou Feng Chen Yingzuo Bi Qingmei Xie Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015 Scientific Reports |
author_facet |
Keyu Feng Feng Wang Yu Xue Qingfeng Zhou Feng Chen Yingzuo Bi Qingmei Xie |
author_sort |
Keyu Feng |
title |
Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015 |
title_short |
Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015 |
title_full |
Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015 |
title_fullStr |
Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015 |
title_full_unstemmed |
Epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern China during the period from 2013–2015 |
title_sort |
epidemiology and characterization of avian infectious bronchitis virus strains circulating in southern china during the period from 2013–2015 |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2017-07-01 |
description |
Abstract Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013–2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. Nucleotide homologies ranged from 63.1–99.9% and amino acid homologies ranging from 60.2–100%. At least seven IBV genotypes were co-circulating in commercial chicken farms in southern China. The IBV isolates were genetically diverse and underwent continuing evolution. The QX-type, TW I-type, and 4/91-type were the most common genotypes during the three-year observation period and accounted for 88.8% of the isolated strains. Notably, the prevalence of the TW I-type strains has been increasing in recent years and has become the most common genotype in China. The emergence of variant IBV strains can be attributed to recombination. Serologic analysis and antigenic 3D cartography of 4 reference and 14 field isolated strains indicated the surveyed IBVs had diverse serology types and that the serotype of the isolated QX-type and TW I-type strains was distinct from the vaccines strains. Therefore, long-term continuing surveillance is necessary for IBV prevention and control. |
url |
https://doi.org/10.1038/s41598-017-06987-2 |
work_keys_str_mv |
AT keyufeng epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 AT fengwang epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 AT yuxue epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 AT qingfengzhou epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 AT fengchen epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 AT yingzuobi epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 AT qingmeixie epidemiologyandcharacterizationofavianinfectiousbronchitisvirusstrainscirculatinginsouthernchinaduringtheperiodfrom20132015 |
_version_ |
1724396391566934016 |