Clinical effect analysis of different surgical treatment of primary pterygium

• Main Authors: Yan Zhang, Ling-Pu Kong, Cui Wang, Jun-Yan Ma, Jie Lü
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-02-01
• Series: Guoji Yanke Zazhi
• Subjects: pterygium; amniotic membrane transplantation; autologous corneal limbus stem cell transplantation; mitomycin C
• Online Access: http://ies.ijo.cn/cn_publish/2015/2/201502052.pdf

AIM: To compare and analyze the clinical treatment effect of primary pterygium with amniotic membrane transplantation, autologous corneal limbus stem cell transplantation and intraoperative application of 0.2g/L mitomycin C. <p>METHODS: Retrospective analysis of 232 patients who were underwent primary pterygium surgery was performed. Eighty-two cases were treated with amniotic membrane transplantation, 90 with autologous corneal limbus stem cell transplantation, and 60 with intraoperative application of 0.2g/L mitomycin C. The postoperative recurrence and complications of three operative methods were compared. <p>RESULTS: The recurrence rate of autologous corneal limbus stem cell transplantation and intraoperative application of 0.2g/L mitomycin C was lower than that of amniotic membrane transplantation(<i>P</i><0.05). The recurrence rate between autologous corneal limbus stem cell transplantation and intraoperative application of 0.2g/L mitomycin C had no difference(<i>P</i>>0.05). Corneal epithelium defect, tears and photophobia were higher in 0.2g/L mitomycin C group(<i>P</i><0.05), which were no statistical difference between autologous corneal limbus stem cell transplantation and amniotic membrane transplantation(<i>P</i>>0.05). Conjunctival congestion and subconjunctival hemorrhage in three groups had no statistical difference(<i>P</i>>0.05). <p>CONCLUSION: Compared with other two operative methods,autologous corneal limbus stem cell transplantation for primary pterygium has the advantages of lower recurrence rate and less complications.