Applicability of an Experimental Grade of Hydroxypropyl Methylcellulose Acetate Succinate as a Carrier for Formation of Solid Dispersion with Indomethacin
The transformation of a crystalline drug into an amorphous form is a promising way to enhance the oral bioavailability of poorly water-soluble drugs. Blending of a carrier, such as a hydrophilic polymer, with an amorphous drug is a widely used method to produce a solid dispersion and inhibit crystal...
Main Authors: | Hiroshi Ueda, Yuya Hirakawa, Hironori Tanaka, Tetsuya Miyano, Katsuji Sugita |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/3/353 |
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