Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects

<p>Abstract</p> <p>Background</p> <p>With the increasing use of nanomaterials, the need for methods and assays to examine their immunosafety is becoming urgent, in particular for nanomaterials that are deliberately administered to human subjects (as in the case of nanom...

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Bibliographic Details
Main Authors: Rossi François, Lucchesi Davide, Leppens Hilde, Favilli Flavia, Ooms Daniëlla, Kohl Yvonne, Pfaller Tobias, Ponti Jessica, Stritzinger René, Colognato Renato, Italiani Paola, Casals Eudald, Oostingh Gertie J, Nelissen Inge, Thielecke Hagen, Puntes Victor F, Duschl Albert, Boraschi Diana
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/8/1/8

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