Analysis of Essential Viral Gene Functions after Highly Efficient Adenofection of Cells with Cloned Human Cytomegalovirus Genomes

Analysis of Essential Viral Gene Functions after Highly Efficient Adenofection of Cells with Cloned Human Cytomegalovirus Genomes

Human cytomegalovirus (HCMV) has a large 240 kb genome that may encode more than 700 gene products with many of them remaining uncharacterized. Mutagenesis of bacterial artificial chromosome (BAC)-cloned CMV genomes has greatly facilitated the analysis of viral gene functions. However, the roles of...

Full description

Bibliographic Details
Main Authors: Endrit Elbasani, Ildar Gabaev, Lars Steinbrück, Martin Messerle, Eva Maria Borst
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Viruses
Subjects:
human cytomegalovirus
bacterial artificial chromosomes
essential viral genes
transfection
adenovirus
Online Access:http://www.mdpi.com/1999-4915/6/1/354

Internet

http://www.mdpi.com/1999-4915/6/1/354

Similar Items