Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function

Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function

Unconventional myosins, linked to deafness, are also proposed to play a role in retinal cell physiology. However, their direct role in photoreceptor function remains unclear. We demonstrate that systemic loss of the unconventional myosin MYO1C in mice, specifically causes rhodopsin mislocalization,...

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Bibliographic Details
Main Authors: Ashish K. Solanki, Manas R. Biswal, Stephen Walterhouse, René Martin, Altaf A. Kondkar, Hans-Joachim Knölker, Bushra Rahman, Ehtesham Arif, Shahid Husain, Sandra R. Montezuma, Deepak Nihalani, Glenn Prazere Lobo
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
motor protein
myosin 1C
photoreceptor
rhodopsin
retina
outer segments
Online Access:https://www.mdpi.com/2073-4409/10/6/1322

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