Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis

During the conduct of clinical trials, it is not uncommon to have protocol violations or inability to assess outcomes. This article in our series on common pitfalls in statistical analysis explains the complexities of analyzing results from such trials and highlights the importance of "intentio...

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Main Authors: Priya Ranganathan, C S Pramesh, Rakesh Aggarwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Perspectives in Clinical Research
Subjects:
Online Access:http://www.picronline.org/article.asp?issn=2229-3485;year=2016;volume=7;issue=3;spage=144;epage=146;aulast=Ranganathan
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spelling doaj-d499cf7a531b478598801c94a349cb352020-11-24T20:53:01ZengWolters Kluwer Medknow PublicationsPerspectives in Clinical Research2229-34852016-01-017314414610.4103/2229-3485.184823Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysisPriya RanganathanC S PrameshRakesh AggarwalDuring the conduct of clinical trials, it is not uncommon to have protocol violations or inability to assess outcomes. This article in our series on common pitfalls in statistical analysis explains the complexities of analyzing results from such trials and highlights the importance of "intention-to-treat" analysis.http://www.picronline.org/article.asp?issn=2229-3485;year=2016;volume=7;issue=3;spage=144;epage=146;aulast=RanganathanBiasbiostatisticsintention-to-treat analysis
collection DOAJ
language English
format Article
sources DOAJ
author Priya Ranganathan
C S Pramesh
Rakesh Aggarwal
spellingShingle Priya Ranganathan
C S Pramesh
Rakesh Aggarwal
Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis
Perspectives in Clinical Research
Bias
biostatistics
intention-to-treat analysis
author_facet Priya Ranganathan
C S Pramesh
Rakesh Aggarwal
author_sort Priya Ranganathan
title Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis
title_short Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis
title_full Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis
title_fullStr Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis
title_full_unstemmed Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis
title_sort common pitfalls in statistical analysis: intention-to-treat versus per-protocol analysis
publisher Wolters Kluwer Medknow Publications
series Perspectives in Clinical Research
issn 2229-3485
publishDate 2016-01-01
description During the conduct of clinical trials, it is not uncommon to have protocol violations or inability to assess outcomes. This article in our series on common pitfalls in statistical analysis explains the complexities of analyzing results from such trials and highlights the importance of "intention-to-treat" analysis.
topic Bias
biostatistics
intention-to-treat analysis
url http://www.picronline.org/article.asp?issn=2229-3485;year=2016;volume=7;issue=3;spage=144;epage=146;aulast=Ranganathan
work_keys_str_mv AT priyaranganathan commonpitfallsinstatisticalanalysisintentiontotreatversusperprotocolanalysis
AT cspramesh commonpitfallsinstatisticalanalysisintentiontotreatversusperprotocolanalysis
AT rakeshaggarwal commonpitfallsinstatisticalanalysisintentiontotreatversusperprotocolanalysis
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