MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells
Summary: Malignant brain tumors are the leading cause of cancer-related deaths in children. Primitive neuroectodermal tumors of the CNS (CNS-PNETs) are particularly aggressive embryonal tumors of unknown cellular origin. Recent genomic studies have classified CNS-PNETs into molecularly distinct subg...
Main Authors: | Katarzyna Modzelewska, Elena F. Boer, Timothy L. Mosbruger, Daniel Picard, Daniela Anderson, Rodney R. Miles, Mitchell Kroll, William Oslund, Theodore J. Pysher, Joshua D. Schiffman, Randy Jensen, Cicely A. Jette, Annie Huang, Rodney A. Stewart |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-10-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716313547 |
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