Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice

Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice

Tumor-associated macrophages (TAMs) as immune cells within the tumor microenvironment have gained much interests as basic science regarding their roles in tumor progression unfolds. Better understanding of their polarization into pro-tumoral phenotype to promote tumor growth, tumor angiogenesis, imm...

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Bibliographic Details
Main Authors: Sharmilla Devi Jayasingam, Marimuthu Citartan, Thean Hock Thang, Anani Aila Mat Zin, Kai Cheen Ang, Ewe Seng Ch'ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
tumor-associated macrophages
M1
M2
immunohistochemistry
CD68
CD163
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01512/full

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