Modelo de detección de anticuerpos neutralizantes contra IFN-β mediante citometría de flujo

Modelo de detección de anticuerpos neutralizantes contra IFN-β mediante citometría de flujo

Introducción. El interferón beta (IFN-β) se usa para tratar la forma recaída-remisión de la esclerosis múltiple. Sin embargo, el uso de proteínas recombinantes como medicamentos puede generar la producción de anticuerpos, disminuyendo así la efectividad del tratamiento. Objetivo. Estandarizar una t...

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Bibliographic Details
Main Authors:	Juan Carlos Villa-Camacho, Juan Camilo Vargas-Zambrano, John Mario González
Format:	Article
Language:	English
Published:	Instituto Nacional de Salud 2012-12-01
Series:	Biomédica: revista del Instituto Nacional de Salud
Subjects:	Antibodies, neutralizing K562 cells, flow cytometry, multiple sclerosis, interferon-beta.
Online Access:	http://www.revistabiomedica.org/index.php/biomedica/article/view/637

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