Characteristics of Malignant Pleural Effusion Resident CD8<sup>+</sup> T Cells from a Heterogeneous Collection of Tumors

Characteristics of Malignant Pleural Effusion Resident CD8<sup>+</sup> T Cells from a Heterogeneous Collection of Tumors

While T cell-based cancer immunotherapies have shown great promise, there remains a need to understand how individual metastatic tumor environments impart local T cell dysfunction. At advanced stages, cancers that metastasize to the pleural space can result in a malignant pleural effusion (MPE) that...

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Bibliographic Details
Main Authors:	Rajeev Dhupar, Olugbenga T. Okusanya, Seth H. Eisenberg, Sara E. Monaco, Ayana T. Ruffin, Dongyan Liu, James D. Luketich, Udai S. Kammula, Tullia C. Bruno, Michael T. Lotze, Adam C. Soloff
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	International Journal of Molecular Sciences
Subjects:	malignant pleural effusion metastatic cancer T cell response tumor immunosuppression
Online Access:	https://www.mdpi.com/1422-0067/21/17/6178

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