Combined linkage and association studies show that HLA class II variants control levels of antibodies against Epstein-Barr virus antigens.

Over 95% of the adult population worldwide is infected with Epstein-Barr virus (EBV). EBV infection is associated with the development of several cancers, including Hodgkin lymphoma (HL). Elevated levels of anti-EBV antibodies have been associated with increased risk of HL. There is growing evidence...

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Main Authors: Vincent Pedergnana, Laurène Syx, Aurélie Cobat, Julien Guergnon, Pauline Brice, Christophe Fermé, Patrice Carde, Olivier Hermine, Catherine Le-Pendeven, Corinne Amiel, Yassine Taoufik, Alexandre Alcaïs, Ioannis Theodorou, Caroline Besson, Laurent Abel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25025336/pdf/?tool=EBI