A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer

A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer

Cell migration is a key process in cancer metastasis, allowing malignant cells to spread from the primary tumor to distant organs. At the molecular level, migration is the result of several coordinated events involving mechanical forces and cellular signaling, where the second messenger Ca2+ plays a...

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Bibliographic Details
Main Authors: Jimena Canales, Diego Morales, Constanza Blanco, José Rivas, Nicolás Díaz, Ioannis Angelopoulos, Oscar Cerda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Physiology
Subjects:
TRP channels
mechanotransduction
focal adhesion
actin cytoskeletal remodeling
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00757/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00757/full

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