Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Abstract In chronic lymphocytic leukemia (CLL), a diverse set of genetic mutations is embedded in a deregulated epigenetic landscape that drives cancerogenesis. To elucidate the role of aberrant chromatin features, we mapped DNA methylation, seven histone modifications, nucleosome positions, chromat...
Main Authors: | Jan‐Philipp Mallm, Murat Iskar, Naveed Ishaque, Lara C Klett, Sabrina J Kugler, Jose M Muino, Vladimir B Teif, Alexandra M Poos, Sebastian Großmann, Fabian Erdel, Daniele Tavernari, Sandra D Koser, Sabrina Schumacher, Benedikt Brors, Rainer König, Daniel Remondini, Martin Vingron, Stephan Stilgenbauer, Peter Lichter, Marc Zapatka, Daniel Mertens, Karsten Rippe |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-05-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20188339 |
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