Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’

Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’

Lysine acetylation is a post-translational modification that is conserved from bacteria to humans. It is catalysed by the activities of lysine acetyltransferases, which use acetyl-CoA as the acetyl-donor molecule, and lysine deacetylases, which remove the acetyl moiety. Recently, it was reported tha...

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Main Authors: Magdalena Kremer, Nora Kuhlmann, Marius Lechner, Linda Baldus, Michael Lammers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
lysine acetylation
deacetylase
YcgC
Online Access:https://elifesciences.org/articles/37798
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spelling doaj-d53cafe6f72b4a2b9b986d75c487f2d32021-05-05T15:58:31ZengeLife Sciences Publications LtdeLife2050-084X2018-06-01710.7554/eLife.37798Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’Magdalena Kremer0Nora Kuhlmann1Marius Lechner2Linda Baldus3Michael Lammers4https://orcid.org/0000-0003-4168-4640Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, GermanyInstitute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, GermanyInstitute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, GermanyInstitute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, GermanyInstitute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany; Institute of Biochemistry, Synthetic and Structural Biochemistry, University of Greifswald, Greifswald, GermanyLysine acetylation is a post-translational modification that is conserved from bacteria to humans. It is catalysed by the activities of lysine acetyltransferases, which use acetyl-CoA as the acetyl-donor molecule, and lysine deacetylases, which remove the acetyl moiety. Recently, it was reported that YcgC represents a new prokaryotic deacetylase family with no apparent homologies to existing deacetylases (Tu et al., 2015). Here we report the results of experiments which demonstrate that YcgC is not a deacetylase.https://elifesciences.org/articles/37798lysine acetylationdeacetylaseYcgC
collection DOAJ
language English
format Article
sources DOAJ
author Magdalena Kremer
Nora Kuhlmann
Marius Lechner
Linda Baldus
Michael Lammers
spellingShingle Magdalena Kremer
Nora Kuhlmann
Marius Lechner
Linda Baldus
Michael Lammers
Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’
eLife
lysine acetylation
deacetylase
YcgC
author_facet Magdalena Kremer
Nora Kuhlmann
Marius Lechner
Linda Baldus
Michael Lammers
author_sort Magdalena Kremer
title Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’
title_short Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’
title_full Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’
title_fullStr Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’
title_full_unstemmed Comment on ‘YcgC represents a new protein deacetylase family in prokaryotes’
title_sort comment on ‘ycgc represents a new protein deacetylase family in prokaryotes’
publisher eLife Sciences Publications Ltd
series eLife
issn 2050-084X
publishDate 2018-06-01
description Lysine acetylation is a post-translational modification that is conserved from bacteria to humans. It is catalysed by the activities of lysine acetyltransferases, which use acetyl-CoA as the acetyl-donor molecule, and lysine deacetylases, which remove the acetyl moiety. Recently, it was reported that YcgC represents a new prokaryotic deacetylase family with no apparent homologies to existing deacetylases (Tu et al., 2015). Here we report the results of experiments which demonstrate that YcgC is not a deacetylase.
topic lysine acetylation
deacetylase
YcgC
url https://elifesciences.org/articles/37798
work_keys_str_mv AT magdalenakremer commentonycgcrepresentsanewproteindeacetylasefamilyinprokaryotes
AT norakuhlmann commentonycgcrepresentsanewproteindeacetylasefamilyinprokaryotes
AT mariuslechner commentonycgcrepresentsanewproteindeacetylasefamilyinprokaryotes
AT lindabaldus commentonycgcrepresentsanewproteindeacetylasefamilyinprokaryotes
AT michaellammers commentonycgcrepresentsanewproteindeacetylasefamilyinprokaryotes
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