Microstructural White Matter Properties Mediate the Association between APOE and Perceptual Speed in Very Old Persons without Dementia.
Reduced white matter integrity, as indicated by lower fractional anisotropy (FA) and higher mean diffusivity (MD), has been related to poorer perceptual speed (PS) performance. As the ε4 allele has been associated with lower white matter integrity in old age, this represents a potential mechanism th...
Main Authors: | Erika J Laukka, Martin Lövdén, Grégoria Kalpouzos, Goran Papenberg, Lina Keller, Caroline Graff, Tie-Qiang Li, Laura Fratiglioni, Lars Bäckman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4529164?pdf=render |
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