The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent.
Type I interferons (including IFNαβ) are innate cytokines that may contribute to pathogenesis during Mycobacterium tuberculosis (Mtb) infection. To induce IFNβ, Mtb must gain access to the host cytosol and trigger stimulator of interferon genes (STING) signaling. A recently proposed model suggests t...
Main Authors: | Kirsten E Wiens, Joel D Ernst |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-08-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4976988?pdf=render |
Similar Items
-
Type I Interferon Induction by Diverse Strains of the Mycobacterium Tuberculosis Complex
by: Wiens, Kirsten E.
Published: (2017) -
Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains.
by: Dane Parker, et al.
Published: (2014-02-01) -
Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
by: Mihai G Netea, et al.
Published: (2006-08-01) -
Transmission phenotype of Mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology.
by: Sheetal Verma, et al.
Published: (2019-03-01) -
Toll-like Receptor 2-dependent Inhibition of Interferon gamma Signaling by <em>Mycobacterium tuberculosis</em>
by: Pennini, Meghan E.
Published: (2006)