Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii.

The liver stages of Plasmodium parasites are important targets for the development of anti-malarial vaccine candidates and chemoprophylaxis approaches that aim to prevent clinical infection. Analyzing the impact of interventions on liver stages in the murine malaria model system Plasmodium yoelii ha...

Full description

Bibliographic Details
Main Authors: Jessica L Miller, Sara Murray, Ashley M Vaughan, Anke Harupa, Brandon Sack, Michael Baldwin, Ian N Crispe, Stefan H I Kappe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3623966?pdf=render