Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
We report a case of anti-HMGCR myopathy mimicking limb-girdle muscular dystrophy in a 27-year-old male patient with no history of statin intake and presenting with a chronic onset form over 3 years. Treatment with prednisone and methotrexate was initiated with an insufficient response, so intravenou...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2021-06-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/2672 |
| Summary: | We report a case of anti-HMGCR myopathy mimicking limb-girdle muscular dystrophy in a 27-year-old male patient with no history of statin intake and presenting with a chronic onset form over 3 years. Treatment with prednisone and methotrexate was initiated with an insufficient response, so intravenous immunoglobulin was added. One year after initial treatment was started, as levels of creatine kinase (CK) were >1000 U/l, treatment with rituximab was added. Despite a 3-year delay before treatment, muscle strength improved even though CK levels remain elevated. |
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| ISSN: | 2284-2594 |