Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships

Rice (Oryza sativa L.) processing yields ~60 million metric tons of bran annually. Rice genes producing bran metabolites of nutritional and human health importance were assessed across 17 diverse cultivars from seven countries using non-targeted metabolomics, and resulted in 378–430 metabo...

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Main Authors:	Iman Zarei, Emily Luna, Jan E. Leach, Anna McClung, Samuel Vilchez, Ousmane Koita, Elizabeth P. Ryan
Format:	Article
Language:	English
Published:	MDPI AG 2018-10-01
Series:	Metabolites
Subjects:	rice bran rice genes rice cultivars metabolic pathway metabolomics
Online Access:	http://www.mdpi.com/2218-1989/8/4/63

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spelling	doaj-d5a90dda025e4d64bb18f2c26b5856552020-11-25T00:17:36ZengMDPI AGMetabolites2218-19892018-10-01846310.3390/metabo8040063metabo8040063Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite RelationshipsIman Zarei0Emily Luna1Jan E. Leach2Anna McClung3Samuel Vilchez4Ousmane Koita5Elizabeth P. Ryan6Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USADepartment of Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, CO 80523, USADepartment of Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, CO 80523, USAUSDA-Agricultural Research Service, Dale Bumpers National Rice Research Center, Stuttgart, AR 72160, USACenter of Infectious Diseases, Department of Microbiology and Parasitology, Faculty of Medical Sciences, National Autonomous University of Nicaragua, León (UNAN-León), León 21000, NicaraguaLaboratoire de Biologie Moléculaire Appliquée, Campus de Badalabougou, Université des Sciences, des Techniques et des Technologies de Bamako, BP 1805 Bamako, MaliDepartment of Environmental and Radiological Health Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USARice (Oryza sativa L.) processing yields ~60 million metric tons of bran annually. Rice genes producing bran metabolites of nutritional and human health importance were assessed across 17 diverse cultivars from seven countries using non-targeted metabolomics, and resulted in 378–430 metabolites. Gambiaka cultivar had the highest number and Njavara had the lowest number of metabolites. The 71 rice bran compounds of significant variation by cultivar included 21 amino acids, seven carbohydrates, two metabolites from cofactors and vitamins, 33 lipids, six nucleotides, and two secondary metabolites. Tryptophan, α-ketoglutarate, γ-tocopherol/β-tocopherol, and γ-tocotrienol are examples of bran metabolites with extensive cultivar variation and genetic information. Thirty-four rice bran components that varied between cultivars linked to 535 putative biosynthetic genes using to the OryzaCyc 4.0, Plant Metabolic Network database. Rice genes responsible for bran composition with animal and human health importance is available for rice breeding programs to utilize in crop improvement.http://www.mdpi.com/2218-1989/8/4/63rice branrice genesrice cultivarsmetabolic pathwaymetabolomics
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Iman Zarei Emily Luna Jan E. Leach Anna McClung Samuel Vilchez Ousmane Koita Elizabeth P. Ryan
spellingShingle	Iman Zarei Emily Luna Jan E. Leach Anna McClung Samuel Vilchez Ousmane Koita Elizabeth P. Ryan Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships Metabolites rice bran rice genes rice cultivars metabolic pathway metabolomics
author_facet	Iman Zarei Emily Luna Jan E. Leach Anna McClung Samuel Vilchez Ousmane Koita Elizabeth P. Ryan
author_sort	Iman Zarei
title	Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships
title_short	Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships
title_full	Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships
title_fullStr	Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships
title_full_unstemmed	Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships
title_sort	comparative rice bran metabolomics across diverse cultivars and functional rice gene–bran metabolite relationships
publisher	MDPI AG
series	Metabolites
issn	2218-1989
publishDate	2018-10-01
description	Rice (Oryza sativa L.) processing yields ~60 million metric tons of bran annually. Rice genes producing bran metabolites of nutritional and human health importance were assessed across 17 diverse cultivars from seven countries using non-targeted metabolomics, and resulted in 378–430 metabolites. Gambiaka cultivar had the highest number and Njavara had the lowest number of metabolites. The 71 rice bran compounds of significant variation by cultivar included 21 amino acids, seven carbohydrates, two metabolites from cofactors and vitamins, 33 lipids, six nucleotides, and two secondary metabolites. Tryptophan, α-ketoglutarate, γ-tocopherol/β-tocopherol, and γ-tocotrienol are examples of bran metabolites with extensive cultivar variation and genetic information. Thirty-four rice bran components that varied between cultivars linked to 535 putative biosynthetic genes using to the OryzaCyc 4.0, Plant Metabolic Network database. Rice genes responsible for bran composition with animal and human health importance is available for rice breeding programs to utilize in crop improvement.
topic	rice bran rice genes rice cultivars metabolic pathway metabolomics
url	http://www.mdpi.com/2218-1989/8/4/63
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Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene–Bran Metabolite Relationships

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