Patient hematology during hospitalization for viral pneumonia caused by SARS-CoV-2 and non-SARS-CoV-2 agents: a retrospective study

• Main Authors: Bingke Bai, Zhe Xu, Yan Hu, Mengmeng Qu, Juan Cheng, Shengdong Luo, Zengtao Yao, Hongyan Gao, Yenv Ma, Rong Gao, Jun Hou, Shaojie Xin, Panyong Mao
• Format: Article
• Language: English
• Published: BMC 2021-05-01
• Series: European Journal of Medical Research
• Subjects: Hematology; SARS-CoV-2; COVID-19; Adenovirus; H1N1
• Online Access: https://doi.org/10.1186/s40001-021-00515-9

Abstract Background Hematological comparison of coronavirus disease (COVID-19) and other viral pneumonias can provide insights into COVID-19 treatment. Methods In this retrospective case–control single-center study, we compared the data of 126 patients with viral pneumonia during different outbreaks [severe acute respiratory syndrome (SARS) in 2003, influenza A (H1N1) in 2009, human adenovirus type 7 in 2018, and COVID-19 in 2020]. Results One of the COVID-19 characteristics was a continuous decline in the hemoglobin level. The neutrophil count was related to the aggravation of COVID-19 and SARS. Thrombocytopenia occurred in patients with SARS and severe COVID-19 even at the recovery stage. Lymphocytes were related to the entire course of adenovirus infection, recovery of COVID-19, and disease development of SARS. Conclusions Dynamic changes in hematological counts could provide a reference for the pathogenesis and prognosis of pneumonia caused by respiratory viruses in clinics.