Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application
Heparin is a promising antimalarial drug due to its activity in inhibiting <i>Plasmodium</i> invasion of red blood cells and to the lack of resistance evolution by the parasite against it, but its potent anticoagulant activity is preventing the advance of heparin along the clinical pipel...
Main Authors: | Elena Lantero, Carlos Raúl Aláez-Versón, Pilar Romero, Teresa Sierra, Xavier Fernàndez-Busquets |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/12/9/825 |
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