Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats

Several studies have suggested that testosterone exerts a growth-promoting effect in the heart. Limited data are available regarding interactions between possible endocrine/paracrine effects in response to exercise training. Therefore, we examined supraphysiological testosterone-induced heart hypert...

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Main Authors: Żebrowska Aleksandra, Sadowska-Krępa Ewa, Jagsz Sławomir, Kłapcińska Barbara, Langfort Józef
Format: Article
Language:English
Published: De Gruyter 2017-04-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2017-0014
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spelling doaj-d5c3c30d0a43465ba3003a0b8b73d8352021-09-05T20:42:21ZengDe GruyterOpen Life Sciences2391-54122017-04-0112112012710.1515/biol-2017-0014biol-2017-0014Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male ratsŻebrowska Aleksandra0Sadowska-Krępa Ewa1Jagsz Sławomir2Kłapcińska Barbara3Langfort Józef4Department of Physiological and Medical Sciences, Academy of Physical Education, Katowice, PolandDepartment of Physiological and Medical Sciences, Academy of Physical Education, Katowice, PolandDepartment of Physiological and Medical Sciences, Academy of Physical Education, Katowice, PolandDepartment of Physiological and Medical Sciences, Academy of Physical Education, Katowice, PolandDepartment of Experimental Pharmacology, Mossakowski Medical Research Center, Polish Academy of Sciences, Warsaw, PolandSeveral studies have suggested that testosterone exerts a growth-promoting effect in the heart. Limited data are available regarding interactions between possible endocrine/paracrine effects in response to exercise training. Therefore, we examined supraphysiological testosterone-induced heart hypertrophy and cardiac insulin-like growth factor (IGF)-1 content in sedentary and exercise-trained rats.https://doi.org/10.1515/biol-2017-0014heartgrowth factorsanabolic steroidsexercise training
collection DOAJ
language English
format Article
sources DOAJ
author Żebrowska Aleksandra
Sadowska-Krępa Ewa
Jagsz Sławomir
Kłapcińska Barbara
Langfort Józef
spellingShingle Żebrowska Aleksandra
Sadowska-Krępa Ewa
Jagsz Sławomir
Kłapcińska Barbara
Langfort Józef
Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats
Open Life Sciences
heart
growth factors
anabolic steroids
exercise training
author_facet Żebrowska Aleksandra
Sadowska-Krępa Ewa
Jagsz Sławomir
Kłapcińska Barbara
Langfort Józef
author_sort Żebrowska Aleksandra
title Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats
title_short Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats
title_full Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats
title_fullStr Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats
title_full_unstemmed Cardiac hypertrophy and IGF-1 response to testosterone propionate treatment in trained male rats
title_sort cardiac hypertrophy and igf-1 response to testosterone propionate treatment in trained male rats
publisher De Gruyter
series Open Life Sciences
issn 2391-5412
publishDate 2017-04-01
description Several studies have suggested that testosterone exerts a growth-promoting effect in the heart. Limited data are available regarding interactions between possible endocrine/paracrine effects in response to exercise training. Therefore, we examined supraphysiological testosterone-induced heart hypertrophy and cardiac insulin-like growth factor (IGF)-1 content in sedentary and exercise-trained rats.
topic heart
growth factors
anabolic steroids
exercise training
url https://doi.org/10.1515/biol-2017-0014
work_keys_str_mv AT zebrowskaaleksandra cardiachypertrophyandigf1responsetotestosteronepropionatetreatmentintrainedmalerats
AT sadowskakrepaewa cardiachypertrophyandigf1responsetotestosteronepropionatetreatmentintrainedmalerats
AT jagszsławomir cardiachypertrophyandigf1responsetotestosteronepropionatetreatmentintrainedmalerats
AT kłapcinskabarbara cardiachypertrophyandigf1responsetotestosteronepropionatetreatmentintrainedmalerats
AT langfortjozef cardiachypertrophyandigf1responsetotestosteronepropionatetreatmentintrainedmalerats
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