Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer
Objective: To observe the effect of Yunpi Huoxue soup combined with chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer. Methods: A total of 94 cases patients with advanced gastric cancer were randomly divided into the treatment group (49 cases) an...
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doaj-d5cb803a836940078009ee93c235779c2020-11-25T01:23:35ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372016-08-012216106109Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancerPei Xiang0Wei-Min Zhu1Department of oncology, traditional Chinese medicine and Western medicine, second Chinese Medicine Hospital of Wuxi, Jiangsu Wuxi 214000Department of oncology, traditional Chinese medicine and Western medicine, second Chinese Medicine Hospital of Wuxi, Jiangsu Wuxi 214000Objective: To observe the effect of Yunpi Huoxue soup combined with chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer. Methods: A total of 94 cases patients with advanced gastric cancer were randomly divided into the treatment group (49 cases) and the control group (45 cases) according to the results of the draw. The control group was given chemotherapy, the treatment group was given Yunpi Huoxue soup on the basis of the control group. Treated for 6 weeks, observed the changes of T cell subsets (CD3, CD4, CD8 and CD4/CD8) and nutrition indexes: total protein (TP), albumin (ALB), prealbumin (PA) and transferrin (TRF) in the two groups. Results: After treatment, CD3, CD4, CD8 and CD4/CD8 in the treatment group were (57.38±4.03), (31.63±4.26), (30.82±3.52) and (1.16±0.20 ) respectively, there were no significant differences compared with before treatment; After treatment, the levels of CD3, CD4, CD8 and CD4/CD8 in the control group were significantly lower than those before treatment, and the differences were statistically significant; After treatment, the levels of CD3, CD4, CD8 and CD4/CD8 in the treatment group were significant higher than those in the control group after treatment, and the differences were statistically significant. After treatment, TP, ALB, PA and TRF in the treatment group were(54.22±5.93) g/L, (32.47±4.97) g/L, (2.52±0.43) g/L and (1.66±0.40) g/L respectively, there were no significant differences compared with before treatment; After treatment, the levels of TP, ALB, PA and TRF in the control group were significantly lower than those before treatment; After treatment, the levels of TP, ALB, PA and TRF in the treatment group were significant higher than those in the control group after treatment, and the differences were statistically significant. Conclusion: When chemotherapy for patients with advanced gastric cancer, Yunpi Huoxue soup is helpful to maintain the immune function and nutritional status.http://www.hnykdxxb.com/PDF/201616/28.pdfAdvanced gastric cancerYunpi Huoxue soupT cell subsetsNutritional status |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pei Xiang Wei-Min Zhu |
spellingShingle |
Pei Xiang Wei-Min Zhu Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer Journal of Hainan Medical University Advanced gastric cancer Yunpi Huoxue soup T cell subsets Nutritional status |
author_facet |
Pei Xiang Wei-Min Zhu |
author_sort |
Pei Xiang |
title |
Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer |
title_short |
Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer |
title_full |
Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer |
title_fullStr |
Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer |
title_full_unstemmed |
Effect of Yunpi Huoxue soup combined chemotherapy on T lymphocyte subsets and nutritional status in patients with advanced gastric cancer |
title_sort |
effect of yunpi huoxue soup combined chemotherapy on t lymphocyte subsets and nutritional status in patients with advanced gastric cancer |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2016-08-01 |
description |
Objective: To observe the effect of Yunpi Huoxue soup combined with chemotherapy on T
lymphocyte subsets and nutritional status in patients with advanced gastric cancer. Methods:
A total of 94 cases patients with advanced gastric cancer were randomly divided into the
treatment group (49 cases) and the control group (45 cases) according to the results of the draw.
The control group was given chemotherapy, the treatment group was given Yunpi Huoxue soup
on the basis of the control group. Treated for 6 weeks, observed the changes of T cell subsets
(CD3, CD4, CD8 and CD4/CD8) and nutrition indexes: total protein (TP), albumin (ALB),
prealbumin (PA) and transferrin (TRF) in the two groups. Results: After treatment, CD3,
CD4, CD8 and CD4/CD8 in the treatment group were (57.38±4.03), (31.63±4.26), (30.82±3.52)
and (1.16±0.20 ) respectively, there were no significant differences compared with before
treatment; After treatment, the levels of CD3, CD4, CD8 and CD4/CD8 in the control group
were significantly lower than those before treatment, and the differences were statistically
significant; After treatment, the levels of CD3, CD4, CD8 and CD4/CD8 in the treatment group
were significant higher than those in the control group after treatment, and the differences
were statistically significant. After treatment, TP, ALB, PA and TRF in the treatment group
were(54.22±5.93) g/L, (32.47±4.97) g/L, (2.52±0.43) g/L and (1.66±0.40) g/L respectively,
there were no significant differences compared with before treatment; After treatment, the
levels of TP, ALB, PA and TRF in the control group were significantly lower than those before
treatment; After treatment, the levels of TP, ALB, PA and TRF in the treatment group were
significant higher than those in the control group after treatment, and the differences were
statistically significant. Conclusion: When chemotherapy for patients with advanced gastric
cancer, Yunpi Huoxue soup is helpful to maintain the immune function and nutritional status. |
topic |
Advanced gastric cancer Yunpi Huoxue soup T cell subsets Nutritional status |
url |
http://www.hnykdxxb.com/PDF/201616/28.pdf |
work_keys_str_mv |
AT peixiang effectofyunpihuoxuesoupcombinedchemotherapyontlymphocytesubsetsandnutritionalstatusinpatientswithadvancedgastriccancer AT weiminzhu effectofyunpihuoxuesoupcombinedchemotherapyontlymphocytesubsetsandnutritionalstatusinpatientswithadvancedgastriccancer |
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