RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy
High-throughput sequencing (HTS) has the potential to decipher the diversity of T cell repertoires and their dynamics during immune responses. Applied to T cell subsets such as T effector and T regulatory cells, it should help identify novel biomarkers of diseases. However, given the extreme diversi...
Main Authors: | Wahiba Chaara, Ariadna Gonzalez-Tort, Laura-Maria Florez, David Klatzmann, Encarnita Mariotti-Ferrandiz, Adrien Six |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-05-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2018.01038/full |
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